1024 THE IMPACT OF FRAILTY ON 30-DAY MORTALITY FOLLOWING PRIMARY HIP AND KNEE ARTHROPLASTY DUE TO OSTEOARTHRITIS

Abstract Introduction We determined the association between frailty and 30-day mortality following total hip knee arthroplasty (THA/TKA) due to osteoarthritis also impact of THA/TKA on compared a control population. Method used linked primary secondary care data Office for National Statistics data. Frailty was assessed using electronic index categorised as fit, mild, moderate, severe frailty. The Cox regression, adjusted year birth, sex, quintile multiple deprivation surgery. Mortality population who had but no previous THA/TKA, matched deprivation. Results 103,563 cases THA, 125,367 TKA, controls contributed Among those surgery, increased with increasing frailty; hazard ratio (HR) (95% CI) among severely frail vs fit: 2.85 (1.84, 4.39); 2.14 (1.29, 3.53). Compared fit did not have higher people THA respectively, HR 1.60 (1.15, 2.21) 2.98 (1.81, 4.89). There was, however, statistically significant difference in moderate same category. Conclusion A healthy surgery (selection) effect may impacted comparison